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  • Molecular Manipulation with Atomic Force Microscopy

    Molecular Manipulation with Atomic Force Microscopy
    Anne-Sophie Duwez, Nicolas Willet

    Baker. and. associates. in. 2003. with. the. introduction. of. Top7. (Kuhlman.et al.. 2003)..The.fold.that.constitutes.Top7.was.computationally.designed. out.of. sequence.pairs.identified.to.be.stable.(Figure.2.5B)..Out.of.172.structural. models  …

  • Issues in Applied Computing: 2011 Edition

    Issues in Applied Computing: 2011 Edition

    extreme pH and temperature conditions Current study results from the report, ' Molecular basis of the structural stability of a Top7-based scaffold at extreme pH and temperature conditions,' have been published. “The development of stable …

  • Protein Engineering Handbook

    Protein Engineering Handbook
    Stefan Lutz, Uwe Theo Bornscheuer

    since Top7 is so stable and has seven secondary structural elements, it is likely that it can form substructures that are also relatively stable, leading to populated folding intermediates [27]. However, as many of the mutations that were tested …

  • Advances in Bioinformatics and Computational Biology

    Advances in Bioinformatics and Computational Biology
    João C. Setubal, Nalvo F. Almeida

    Influence of Scaffold Stability and Electrostatics on Top7-Based Engineered Helical HIV-1 Epitopes Isabelle F.T. Viana1,2,3, Rafael Dhalia4, Marco A. Krieger3, Ernesto T.A. Marques2,4, and Roberto D. Lins1 1 Department of Fundamental …

  • Comprehensive Nanoscience and Technology

    Comprehensive Nanoscience and Technology

    The ultimate example of a nonmechanical protein of significant mechanical stability is the computationally designed protein Top7 [117]. Top7 is a de novo designed protein and, thus, does not have any mechanical or biological function [ 120].

  • 싱가폴호텔 센토사 Top7

    싱가폴호텔 센토사 Top7
    조명화(B급여행)

    싱가폴호텔. 센토사. Top7. 지은이 조명화(B급여행) 출판사 테마여행신문 TTN Theme Travel News Korea 출판일 24-MAR-2016 판매가격 7,700 원(Korea WON/ KRW) ISBN 9791158840822 이메일 …

  • Privacy-Aware Knowledge Discovery

    Privacy-Aware Knowledge Discovery
    Francesco Bonchi, Elena Ferrari

    18.5 Top5 Top7 Top9 BE = 14.7% UETop5 = 20.4%, UE Top7 = 21.5%, 18.0 UE Top9 = 22.4% 14.5 15.0 15.5 16.0 16.5 17.0 17.5 20 60 100140180300500700900 Threshold k AE( % ) tive than breaking it into multiple QIDs. For this reason …

  • Crossroads Semantics

    Crossroads Semantics
    Hilke Reckman, Lisa L.S. Cheng, Maarten Hijzelendoorn, Rint Sybesma

    For instance, the Top7 verbs together have a bias of 53.4% (= (52,942/99,201)* 100) in favour of MAIN-FIN. This average is weighted for frequency of the underlying individual verb biases. In the second procedure, one first computes the bias …

  • Quantitative Social Science

    Quantitative Social Science
    Kosuke Imai

    … regions = "California") points(x = cal.cities$long[top7], y = cal.cities$lat[top7], pch = 19) ## add a constant to longitude to avoid overlapping with circles text(x = cal.cities$long[top7] + 2.25, y = cal.cities$lat[top7], label = cal.cities$name[top7])  …

  • Agents and Artificial Intelligence

    Agents and Artificial Intelligence
    Joaquim Filipe, Ana Fred

    For evidence groups, we differentiate between the best performing evidence types from our previous work (Top7), all evidence types (All), and all possible evidence types without the Top7 (All w/o Top7). For each search experiment, we  …

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